William Canestaro – Startup Investor Profile

General Info

William Canestaro, Ph.D., Managing Director at Washington Research Foundation/WRF Capital, invests in biotechnology startups in Washington with a focus on long-term success and companies at every stage of growth. His previous investments include 25 investments in 19 Washington-based companies like 2Morrow, A-Alpha Bio, and Icosavax. Dr. Canestaro has a strong professional background in venture capitalism, health economics, and meta-epidemiology. He utilizes his expertise to manage the Foundation’s biotech and engineering VC portfolio, supporting the Washington ecosystem. The investment check size by WRF Capital under his leadership has been significant, leading the biotechnology investment team. Dr. Canestaro is committed to fostering collaboration and partnership within the biotechnology industry.
Location: Seattle, Washington
Country: United States of America
Industries: life sciences, biomedical technologies, medical devices, digital health, scientific instrumentation, consumer technology, software, advanced materials
Investment Regions:
Investment Stages: pre-seed, seed

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🤖 AI Activity Report

Status: very-active

AI Reasoning: Search results show William (Will) Canestaro activity in 2025 (LinkedIn post June 19, 2025) and ongoing role at WRF Capital; WRF has portfolio investments including Icosavax and A-Alpha Bio. Presence of activity in mid-2025 indicates a most recent known investment within less than 6 months relative to the evaluation date, and shows involvement with startups such as Icosavax.

Angel activity thresholds:
Low Activity – Only known angel investments more than 12 months ago.
Active – Known angel investments between the last 12 and 6 months.
Very Active – Known angel investments in the last 6 months.



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