General Info
Paul Sethi is a seasoned investor with a focus on AI, digital bioprocessing, and health technologies. His previous investments include UniKey, SmarterX, and Mealco in the Business/Productivity Software and Media sectors. Dr. Sethi is a prominent orthopedic surgeon known for his sports medicine expertise, serving in various medical societies. His investment check size ranges from $300K to $600K, with a sweet spot at $450K. Dr. Sethi’s collaborative style aligns with introspective and relational approaches, emphasizing deep work, human connections, and visual engagement.
Location: New York, NY
Country: United States of America
Industries:
Investment Regions: NA, OC
Investment Stages: pre-seed, seed
angel-individual
NA, OC
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🤖 AI Activity Report
Status: very-active
AI Reasoning: Search results and Paul Sethi’s profile pages (Trajectory Ventures, VentureLab, LinkedIn, Bloomberg) show ongoing investing activity and recent public engagement. A YouTube Investor Connect episode posted recently (Oct 2025) and his active social posts indicate recent investments; profiles list portfolio companies and ongoing investing roles. Given evidence of activity within the last 6 months (mentions and posts in mid-to-late 2025), classify as very-active.
Angel activity thresholds:
Low Activity – Only known angel investments more than 12 months ago.
Active – Known angel investments between the last 12 and 6 months.
Very Active – Known angel investments in the last 6 months.
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