Matt Mcilwain – Startup Investor Profile

General Info

Matt McIlwain is the Managing Director at Madrona Venture Group. He focuses on a broad range of software and data-driven companies with an emphasis on cloud computing, dataware, and intelligent applications. Madrona primarily invests in seed and Series A rounds. Their geographic preferences include Western Europe, Northern America, and the United States. Matt’s previous investments include companies like Isilon Systems. He brings over 25 years of experience in investing in early-stage technology companies. Madrona’s investment check sizes range from $500,000 to $8 million for early-stage startups. Matt McIlwain is known for his professional career at Madrona and his track record in supporting innovative and valuable companies. His partnership and collaboration styles involve working closely with entrepreneurs from the early stages to full company growth.
Location: Seattle, Washington
Country: United States of America
Industries: AI & Intelligent Apps, AI-Enabled Biotech, Consumer & Marketplace, Data & Infrastructure, Deep Tech, Developer Platforms & Tools, Enterprise Apps, Security
Investment Regions: EU, NA
Investment Stages: pre-seed, seed

angel-individual
EU, NA

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🤖 AI Activity Report

Status: very-active

AI Reasoning: Search results and the Signal profile show multiple investments by Matt McIlwain in 2025, including Synthesize Bio (Sep 2025) and several Series A/Seed investments earlier in 2025 (e.g., EdgeRunner AI, Yoodli in May 2025). The most recent recorded investment is September 2025 (Synthesize Bio), which is less than 6 months ago from the evaluation date, so tag as very-active.

Angel activity thresholds:
Low Activity – Only known angel investments more than 12 months ago.
Active – Known angel investments between the last 12 and 6 months.
Very Active – Known angel investments in the last 6 months.

Warm Intros from Portfolio Companies

David Shim
Founder
Read AI
Jan Thomas
Founder
Otto
Ali Ansary
Founder
Ozette Technologies
Varun Puri
Founder
Yoodli
Yucheng Low
Founder
XetHub

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