Lyle Berkowitz – Startup Investor Profile

General Info

Lyle Berkowitz, General Partner at 2Flo Ventures, focuses on healthcare services, outcome management, and drug discovery. Previous investments include KeyCare (Chicago), 4D Healthware, and Temprian Therapeutics. With over 25 years of experience as a physician and healthcare innovator, Lyle Berkowitz has a track record of advising and investing in the healthcare industry. The investment check size is not specified. Berkowitz is known for his expertise in virtual care and as a venture investor. Geographically, he is based in Chicago, Illinois, USA.
Location: Chicago, Illinois
Country: United States of America
Industries: healthcare, life sciences, biotech, digital health
Investment Regions:
Investment Stages: pre-seed, seed

angel-individual

Want to start building warm intros with this investor?

Get Started for Free

🤖 AI Activity Report

Status: not-found

AI Reasoning: Searches found biographical and company pages (KeyCare, LinkedIn, profiles) confirming Lyle Berkowitz is active as CEO/GP and involved with KeyCare, but no verifiable public record of a recent external investment (e.g., check into Temprian Therapeutics, 4D Healthware, or other startups with dated funding attributable to him) within the last 12 months was found. KeyCare news and profiles dated 2024-2025 reference leadership roles, not venture investments. Because I could not identify a dated investment event to calculate recency, the appropriate classification is not-found.

Angel activity thresholds:
Low Activity – Only known angel investments more than 12 months ago.
Active – Known angel investments between the last 12 and 6 months.
Very Active – Known angel investments in the last 6 months.

Warm Intros from Portfolio Companies


Founder

Founder

Founder

Founder

Founder

Investment Regions Map

loading map…

Similar Investors

Stage match

aruna devi

Based on Stage
Vertical match

Ralf Dummel

Based on Industry
Other similar investors:

Latest on X (Twitter)



Access all contact details of Lyle Berkowitz

Gain instant access to partner names, verified emails, LinkedIn profiles, and more—all in one place. Dive into their portfolio founders and their LinkedIn information, so you can quickly start your outreach and look for warm intros.

Add custom tags to your investor cards. Label them by investment stage, industry focus, interest level, or any other criteria you want to stay organized.

Trusted by Founders like You

Find your matching investors using AI

Sign up to EasyVC