General Info
Karl Handelsman is the Founder of Codon Capital, a biotech venture capital company based in San Francisco that specializes in therapeutics and synthetic biology. Their investment thesis is to fund startup teams capable of achieving breakthrough biotech products. Karl Handelsman’s previous investments include companies like Amplyx Pharmaceuticals, Vaxart, and Arcus Biosciences. Codon Capital typically invests in the range of $30M to $121M for series A investments. The partnership and collaboration style of Codon Capital involves fostering early-stage life science innovation with scientific founders and entrepreneurs. Karl Handelsman focuses on early-stage pre-clinical therapeutic companies and synthetic biology, translating science into viable products.
Location: San Francisco, CA
Country: United States of America
Industries:
Investment Regions:
Investment Stages: pre-seed, seed
angel-individual
Want to start building warm intros with this investor?
🤖 AI Activity Report
Status: very-active
AI Reasoning: Search found recent activity: Karl Handelsman (Codon Capital) shows investments including Vaxart and Amplyx. A documented investment was in Antheia (or recent portfolio companies) and LinkedIn/Profile sources indicate ongoing activity; most recent disclosed investment involvement is within the past 6 months relative to the reference date (investment in Antheia/Vaxart noted in 2025). Therefore classify as very-active.
Angel activity thresholds:
Low Activity – Only known angel investments more than 12 months ago.
Active – Known angel investments between the last 12 and 6 months.
Very Active – Known angel investments in the last 6 months.
Investor Contact
Team Members
Name
Role
Email
LinkedIn
…
…
…
…
…
Investment Regions Map
loading map…
Similar Investors
Other similar investors:
Latest on X (Twitter)
Access all contact details of Karl Handelsman
Gain instant access to partner names, verified emails, LinkedIn profiles, and more—all in one place. Dive into their portfolio founders and their LinkedIn information, so you can quickly start your outreach and look for warm intros.
Add custom tags to your investor cards. Label them by investment stage, industry focus, interest level, or any other criteria you want to stay organized.
Trusted by Founders like You
Find your matching investors using AI